This collection is extensive in its coverage of material relating to the extended Gregory family. It contains more than 30 volumes of bound lectures representing classes attended and taught by family members whilst studying and working at universities in Aberdeen, Edinburgh, St Andrews and Oxford between the early seventeenth and late nineteenth centuries. There are also 5 boxes of diplomas and other papers associated with the lives and careers of more than 20 family members, 1582 - 1890.
A separate folio contains a selection of personal papers belonging to James Gregory (1753 - 1821), M.D., covering the period 1784 - 1821. Contents include letters, accounts, verses and inscriptions, including epitaphs for family members and public figures. A volume entitled Physician's accounts, Dr Jas Gregorie, 1714 - 1733, which belonged to James Gregory (1674 - 1733), Professor of Medicine, King's College, is also of interest as it lists his patients' accounts, with a separate index of their names, and other misc. entries such as medical orders and accounts.
Other miscellaneous items include a volume of poems and 6 sketch books belonging to Georgina Gregory, 1833 - 1849; a volume of notes, ballads, songs, sonnets and other poems by Mrs Anne Hunter of Leicester Square, 17??, belonging to James Gregory (?1753 - 1821), M.D. of Edinburgh; an annotated copy of Sir Philip Spencer Gregory's Records of the Family of Gregory (London, 1886), belonging to Sir Philip, with MS appendix (23); letters received by Sir Philip Spencer Gregory, concerning the publication of his Records ..., and other family matters with some misc. papers collected by him, 1885 - 1912 (47); volume containing Reflections on the principles of agriculture , and other notes on agricultural topics, including A scheme of a farm by A. Wedderburn Esq. of St Germain's, 16 Jan 1768 , and copies of the minutes of Gordon's Mill Farming Club, mostly in the hand of John Gregory, but also several other unidentified authors, ?1760s (40).; bound volume of papers (including summaries of addresses given), and correspondence re. the Edinburgh Medico-Chirurgical Society, or Institution, 1821 - 1824, in various unknown hands (41); notes for Donald Gregory's History of the Western Highlands of Scotland, 1836 (42); and report books of Algernon Percy and George Percy, Lord Lovaine, by their tutors at Eton, Apr - Dec 1793 (32).