Reports and data relating to a trial of 6-Azauridine in patients with leukaemia by Wilkinson in 1961-1962 as well as reports from other trials. This includes correspondence from C.N. Brown of The Distillers Company (Biochemicals) Limited regarding supplies of azauridine and sending a copy of a paper given at the New York Academy of Sciences in November 1961 by Dr Arnold Welch entitled '6-Azauridine: An Antileukaemic Agent with Unusual Biochemical Properties'; copy of minutes from Consultants' Meeting heled at the Piccadilly Hotel, London on 14 May 1962 and chaired by C.N. Brown in which Wilkinson gives a brief account of his preliminary trials; two individual patient reports of individuals involved in Wilkinson's trial; 8 photographs of cells and chromosomes; a small number of Wilkinson's handwritten notes; and a typescript copy of an article published as Elves, M.W., Buttoo, A.S., Israëls, M.C.G., & Wilkinson J.F., 'Chromosome Changes Caused by 6-Azauridine During Treatment of Acute Myeloblastic Leukaemia', British Medical Journal, 1963, Vo. 1(5324), pp.156-159.
In addition to material relating to Wilkinson's work with 6-Azauridine there are reports from other trials. This includes a report of a visit to Prague to discuss clinical trials of azauridine with representatives of spofa & clinicians in Czechoslovak hospitals by Drs C.N. Brown & D.M. Burley in June & July 1961 with some accompanying case reports. There are also abstracts of Fallon, H.J. & Frei, E. III, 'Clinical & Biochemical Effects of 6 Azauridine in Leukaemia', Proceedings of the American Association of Cancer Research, 1961, 3(224) and Handschumacher, R.E. & Cardoso, S.S., 'Alterations in Human Pyrimidine Metabolism caused by 6-Azauridine', Proceedings of the American Association of Cancer Research, 1961, 3(232).
Seemingly unrelated to the azauridine trials the file also contains a number of photos of equipment and charts relating to the preparation of hog's stomach and a large series of numbered paragraphs or abstracts seemingly relating to a range of different investigations and papers about a variety of instances of leukaemia and its treatment including instances seen in survivors from Hiroshima and Nagasaki.