Medical Research Council: Pernicious Anaemia

Scope and Content

File of correspondence, reports and minutes relating to the clinical testing of commercial preparations of liver and hog's stomach used in the treatment of pernicious anaemia as a result of the Medical Research Council's desire to establish an official standard test based on clinical response. This includes correspondence between Wilkinson and Dr Arthur Landsborough Thomson concerning such issues as the preliminary stages of establishing such a test, cases of food poisoning traced to preparations of desiccated hog's stomach, possible amalgamation of the work of British manufacturers, role of members of the Association for Clinical Pathologists in the scheme, reluctance of manufacturers, and talks with the Boot's Pure Drug Co. The file also includes minutes of the first conference on the issues held in November 1933, an agenda and minutes for the second conference held on 18 January 1934, and an outline of the methods for clinical testing used by the Department of Clinical Investigations and Research at the University of Manchester and Royal Infirmary. There is also one letter from Walter Schlapp of the Department of Physiology at the University of Manchester regarding the criterion of toxicity he has been using for test of extracts sent to him by Wilkinson.

For Wilkinson's research files into the treatment of pernicious anaemia with desiccated hog's stomach see JFW/2/5/1.