The manuscript contains various theological treatises as follows:
- (folio 1) Homiletic discourse and instruction on various themes, under the heading 1581, including, speaking against good men, profiting by preachingand remembering of sermons;
- (folio 4) Homiletic discourse and instruction on various themes, under the heading 1582, including,threatening Gods judgement how it ought to be, heavenly meditations coming and departing suddenly and great zeal and fervency of speach in preaching;
- (folio 52) The acts and speeches of Mr. G. 1584;
- (folio 68) A letter against hardnes of hart, [from R. G.];
- (folio 75) The effect of an exhortation in private to two parties at their contracting before the witnesses, by Maister Hildersam;
- (folio 77) A short treatise wherin (if not al yet) the most necessary points to bee considered about marriage are handled by way of quaestion and answer for the help of the reader; this ends on f. 91 with the note, This discourse was drawen by Mr. Richard Sherwood at the request of the honorable lady Theodosia Dudly, whom it concerned. Followeth a short sum of a speach had by M.T. Car at a contract making between his doughter Marie and Andw Wilmor;
- (folio 96b)Concerning private reading of the word. Arthur Hildersham;
- (folio 99) A.H.; For preparation to prayer...;
- (folio 99) Directions for the order of your prayer;
- (folio 100) A preparation to the Lord's Supper. A.H.;
- (folio 103) A larger preparation to the Lord's Supper in form of a Catechism. A.H.;
- (folio 115) The Catechism contening the sum of both the covnauntes of the law and of the Gospel.
Folios 1-72 comprise sayings by the clergyman Richard Greenham (d 1594). The remainder comprises works attributed to Greenham's student Arthur Hildersham and the theologian Thomas Cartwright. This manuscript has been identified with Arthur Hildersham, but this identification has recently been cast into doubt. According to the scholarly edition published in 1998 (see below), the close correlation between this manuscript and published sayings suggests that the Rylands sayings represent an early, well-established and widely circulated collection of sayings.