Much of this collection is comprised of correspondence which includes letters from Edward M. Wrench to family and friends whilst serving in the Crimean War and the Indian Mutiny. The letters from the Crimea reflect the harsh conditions in the trenches and the difficulties encountered in providing medical care The letters are closely related to other letters which are present amongst the material acquired from Edward Gillam Wrench and many of them are transcribed in the typescript volumes complied by him (see the Wre sub-fonds).
However, most of the letters in the correspondence series were written to Edward M Wrench from family members, medical colleagues, former army colleagues, local dignitaries and many others. These letters include references to family and social news, national and local events , health and medical cases, education and travel, reflecting the wide-ranging interests and activities of Edward M Wrench.
The collection also includes fifty-seven diaries which were kept from 1856 until his death in 1912. These diaries supplement the letters, providing references to events of national and local importance, and to family and medical concerns. Edward M Wrench used his diaries to retain newspaper cuttings, letters, photographs and various ephemeral items. These ephemeral items are of much interest, reflecting not only the life and interests of Edward M Wrench, but also many aspects of life in Victorian England.
The collection also includes genealogical papers mainly relating to the Kirke family, notes and notebooks, printed books and papers, photographs, sketches and miscellaneous and ephemeral items, some of which relate to the Crimea and India and supplement the correspondence from the Crimea and India.