The manuscript bears the bookplate of the Manchester Medical Society which indicates that it was donated to them by Samelson in November 1864. Further annotations show it to have been allocated the reference O 3240 viz. their 1890 library catalogue. On the flyleaf is a list of the contents, namely four different sets of lecture notes taken during 1838-9 session at the University of Berlin. The first three are found in the body of the main manuscript and the fourth are in a separate booklet inserted into the back of the manuscript.
Lectures of Moritz Heinrich Romberg on diseases of the nervous system cover ff.1-216 with the original pagination pp.1-427. A detailed index is provided at the start of these notes.
A second set of lectures from Romberg on diagnostic techniques cover ff.217-258 with the original pagination pp.1-78. Again a detailed index is provided at the beginning and show the lectures to be split into three main sections, namely diagnose der brustkrankheiten, diagnose der unterleibkrankheiten, and diagnose der nervenkrankheiten or the diagnosis of breast diseases, abdominal diseases, and nervous diseases.
Lectures of Anton Ludwig Ernst Horn on mental illnesses cover ff.259-290 with the original pagination pp.1-59. There is a short index at the start of the notes.
The lectures of Emil Osann entitled on the medicinal waters or spawaters of Germany can be found in the separate booklet inserted into the rear of the main manuscript. These notes are not paginated and there is no index.