The volume has the original pagination pp.1425-1665 and ff.127-175 are blank. This is volume 5 of 5 and although the start of each new lecture is clearly marked they are not numbered as they were in the previous 4 volumes. The writing is largely on the recto of each page with occasional notes on the verso and there is a subject index in the rear. A note at the end of the final lecture indicates that they were completed in November 1769.
The contents of the lectures according to the index are: to obviate debility by tonics; exercise; cold; astringents; emollients; warm bathing; sedatives; refrigerants; soporifics; opium; antispasmodics; morbid affections of the fluids; attenuants; inspissants; demulcents; correctors of particular acrimony; evacuants in general; expectorants and apophlegmatizonta; saliva and mercury; diuretics; diaphoretics and sudorifics; menstrual flux and emmenagoga; bloodletting; blisters; issues; emetics; purgatives.
The volume bears the bookplate of the Radford Library, Saint Mary's Hospital, Manchester, which also indicates that it was allocated the reference number Q126 viz. their 1877 catalogue. The volume has since been referenced J6 C66 as part of an alternative system. The spine reads 'Cullen's Institutions Vol.5'.