The volume has the original pagination pp.1073-1423, the writing is largely on the recto of each page with occasional notes on the verso and there is a subject index in the rear. This is volume 4 of 5 and begins part way through lecture 89 and finishes on lecture 113; the start of each new lecture is clearly marked, although they are not dated.
The contents of the lectures according to the index are: acid acrimony; alkalescent acrimony; neutral acrimony; muriatic; ammoniacal; morbi humorum relativi; plethora; different periods of life; death; obesity; macies; want of coagulable lymph; emaciation; motus vitia; general idea of fever; symptoms of diseases; dolor; anxieties; recapitulation; intellectual functions; madness or delirium; fatuity; facultatis motricis symptomata; causes of palsy [paralysis]; diminished excitement; causes and reasons of difficult respiration; asthma; symptom of the motion of the heart; pulse; remote causes of diseases or potentie nocentes; atmosphere; heat; cold; methodus medendi (general remarks, criticism of Dr Boerhaave's rules, criticism of Dr Hoffman's rules); indicationes curatoria; nutrientia.
The volume bears the bookplate of the Radford Library, Saint Mary's Hospital, Manchester, which also indicates that it was allocated the reference number Q126 viz. their 1877 catalogue. The volume has since been referenced J6 C66 as part of an alternative system. The spine reads 'Cullen's Institutions Vol.4'.