The volume bears the bookplate of James Barlow and a note in the front cover indicates that it was acquired by the Manchester Medical Society in 1881 and allocated the reference number D 1590 viz. their 1890 library catalogue and has since been allocated the reference K6 L20 as part of an alternative system. The spine reads 'manuscript lectures No.1'.
There are 291 folios in total; the first 24 being the index, which look to have been added at a later date, and the rest the lecture notes with the original pagination pp.1-534. The lectures are clearly numbered and begin on lecture 45 and finish part way through lecture 71. The fact that the lectures begin on lecture 45 would suggest that there was once another volume that preceded this one that has not survived, however the inscription on the manuscript's spine telling us that it is volume 1 would indicate otherwise, or it has been rebound. There is a pencil note in the back cover that reads '2v = 1/-' suggesting the two volumes have been sold at some point and presumably purchased either by Barlow or by the Medical Society. It is not clear whose lectures the notes are taken from.
The contents according to the index are: arteries, the loss of blood in animals when bled to death, arterial action described, ossification of arteries, bad effects of air on internal parts, external thoracic artery, artery epigastri, anasarca [oedema], quantity of blood in the system, how buboes are produced, the brain, body posture in diseases, bleeding, bronchotomy, crystalline lens, cancer of the mamma, disease of the conglobate glands, croup, veins passing through the dura mater, trepanning [trephining] in epilepsy, anatomy of the eye, structure of the ear, emphysema, death of fish, caution respecting the axilliary gland, pulsation of and rupture of the heart, action of the heart in palsy, how hair is produced, effects of hanging, dislocation of the humerus, division of humeral artery, method of operating in a hernia, impulse of the heart, inoculation, opening of the external jugular vein, instinct, lymphatics, lacteals, description of the lungs, lungs not very sensible organs, the microscope, nervous system affected by inflammation of the arteries, nerves described, oedema of the breast in cancer, pericardium, polypi of the heart, sound, subclavian artery, transfusion, taste, wounds of the tendons, tetanus, quantity of blood in the ventricle, muscular power of veins, how venereal poison is absorbed, and the uniting of a wound.