Most of the content is focused on a consideration of the certain diseases as described and classified by a number of prominent nosologists and can be found on ff.42-258, numbered 268-484. References are made to the classifications and descriptions published by François Boissier de Sauvages de Lacroix (1706-1767), Carl Linnaeus (1707-1778), Rudolf Augustin Vogel (1724-1774), Johan Baptiste Sagar (1732-1813), Gottfried Ploucquet (1716-1790), David Macbride (1726-1778), and William Cullen (1710-1790). The focus of the first half is on diseases classified under Cullen's 'class IV-locales' with a few additions of diseases discussed by others but omitted by Cullen, such as dystocia and aglactatio. The second half instead concentrates on diseases of the order algemata in the class dysaethesiae. There are also a number of loose leaves inserted into the volume which Hull has used to make additions to certain pages, many of which are excerpts and extracts from published sources. It says quite clearly at the head of each of these loose leaves which page they correspond to.
There are a number of notes at the beginning of the manuscript on ff.2-36, numbered 1-69, in a combination of Latin and shorthand entitled 'De Morbis Chirurgicis', but the source of these notes is not immediately evident. There is irregular page numbering throughout.