Pathology Notes

Scope and Content

Notes on pathology made by Moore when he was a medical student at Owens College Manchester. There is no explicit reference to the source of the notes nor is there any attempt to divide them up into individual numbered and dated lectures, instead they are organised under clear subject headings underlined in red ink. However, given the date of the notes and reference to him within, it is likely that they have their origins in the lectures of Sheridan Delépine (1855-1921) who was Professor of Pathology and Morbid Anatomy at the time.

The topics covered in the notes include: general morbid anatomy & physiology and the three factors of multiplication, nutrition, & irritability - disorders of multiplication, proliferative disorders & plastic disorders, teratology (monsters, malformations by defect, malformation by excess); disorders of nutrition or trophic disorders, disorders of the circulation and distribution of the blood, hyperaemia, anaemia, infiltration (oedema, lardaceous, diffuse, pigmentary, fatty, glycogenic); trophic disorders, true or simple atrophy, degeneration (albuminous, fatty, serous, mucoid, colloid, vitreous or hyaline), death [necrosis], general or somatic, local or necrosis, necrosis (coagulation, colliquative necrosis of Ziegler, caseous), gangrene (dry, moist), hypertrophy (functional, congenital, acquired), regeneration and repair; tumours [neoplasms], inflammation (definitions, experimental studies) phagocytosis, inflammatory exudations (serous, sero-fibrinous, purulent, haemorrhagic, putrid), infective inflammation, etiology of tumours, classification of tumours, tumours composed of one tissue only, sarcomata (round cell, spindle cell, myeloid, melanotic, alveolar, angeio), typical connective tissue tumours (fibromata, hard fibroma, soft fibroma, lipomata, gliomata, chondromata, osteomata and odontomata, lymphomata, lymphariogiomata), tumours composed of more than on tissue (myomata, neuromata, epithelial tumours - papillomata, adenomata, cancers, carcinomata), mode of extension of cancers.

For each morbid affection discussed the notes go into detail about regarding the processes behind it, the various forms and causes, descriptions of presentation, the influence of different functions, and sometimes the process of diagnosis. There are also often references to the differing theories associated with some of the disorders, for example the last few pages discuss recent investigations and experiments into the extension of cancers, in particular its inoculability, with reference to work in Iran and France.

There are some illustrations provided as explanatory tools to accompany the notes. Three small sketches of cells in the margins on f.81r, one on f.89v show the effect of vessels to accompanying cells in false membrane, and the other on f.110v shows the state of the lymphatics in macroglossia.