The volume has the original pagination pp.721-1091, ff.1-5 and ff.191-198 are blank, and writing is largely on the recto of each page with occasional notes on the verso. There is no clear numbering or demarcation of lectures as there was in the first two volumes but there is a subject index in the rear.
The contents of the lectures according to the index are: practice in intermittents during fit; neutrals & emetics; remedies out of fit; neutral salts; cold bath; direct stimuli as pepper, nutmeg etc.; astringents, butters; management of intermittents; administration of bark; treatment of continued fevers; removal of spasm & cure of the disease; phlegmasia; symptoms of phlegmon; symptoms of erysipelas; questions relating to internal phlegmasia; general cure of inflammation; bleeding in inflammation; warm bathing; external applications or resolvents; camphor externally applied; refrigerants & astringents external; internal remedies in inflammation; diluents; refrigerants; emetics; opium; purging; particular phlegmasia; ophthalmia; phrenitis [delirium]; angina; croup; pneumonic inflammations; enteritis; peritonitis; gastritis; splenitis; nephritis; cystitis; hysteritis; hepatitis; rheumatism; chronic rheumatism.
The volume bears the bookplate of the Radford Library, Saint Mary's Hospital, Manchester, which also indicates that it was allocated the reference number Q128 viz. their 1877 catalogue. The volume has since been referenced J6 C67 as part of an alternative system. The spine reads 'Cullen's Practice of M. Vol.3'.