The volume has the original pagination pp.1-696, writing is largely on the recto only with occasional notes on the verso, and there is an index in the rear. Lectures on the whole are not numbered or clearly demarcated but clear subject headings are given and the lecture series commenced on 19 February 1812.
The subjects covered according to the index are as follows: acidity of the stomach, actions of the stomach, animal kingdom, animal heat, suspended animation, amenorrhoea, arteries, anasarca [oedema], modus operandi of bark, digestion organs of birds, bile, properties of blood, transmission of blood in the lungs, the brain, comparison of the three kingdoms of nature, comparison of digestive organs of different animals, chylefaction, absorption of chyle, modus operandi of chalybeates, circulation of the blood, chlorosis [hypochromic anaemia], differences between animals and vegetables as regard the vital principles, deglutition, digestion, dropsy [oedema], expulsion of the faeces, expectoration, Dr Fordyce's experiments on temperature, fish more digestible than animal food, gastric juice, ganglion, generation, growth, the heart, imperforate hymen, hunger, incontinence, kidneys, male organs, menstruation, mastication, mesenteric glands, miscarriage [spontaneous abortion], mineral kingdoms, muscular motion, nourishment by glyster, nerves, oedema, pancreatic juice, peristaltic motion of the intestines, structure of the penis, purgatives, pulse of arteries, respiration, retention of urine, senses, sensation, secretion, spleen, structure of the stomach, sympathy, testes, teeth, throat, thoracic duct, temperature of the blood, valves, varicose swellings, vegetable kingdom, veins, vital principles, vomiting, and urine.
The volume bears the bookplate of the Manchester Medical Society which indicates that it was donated to them by Thomas Windsor on 25 June 1877 where it was subsequently allocated the reference GO 3824 viz. their 1890 library catalogue. A note on the flyleaf made by the author reads 'John Windsor, No.2 Plough Court, Lombard Street, July 1811'.