Fawdington qualified LSA and MRCS in 1817 and the following year was appointed physician's clerk at MRI. In 1825 he was appointed lecturer in pathology at Jordon's School of Medicine in Mount Street and gave lectures in anatomy. He was appointed man-midwife to the Manchester and Salford Lying-in Charity (later St Mary's Hospital) in 1826 and held this position until 1839. He helped found the Marsden Street School of Medicine in 1829 and gave lectures in surgical anatomy and pathology, having been recognised as a teacher of anatomy and physiology by the Society of Apothecaries the previous year. Fawdington established a significant anatomy collection at the Marsden Street School and published two books, one of which was a catalogue of this collection. Fawdington was elected to the staff of MRI in 1837. He also had a large practice on Lever Street. He died in 1843 and his anatomy museum was purchased by the MRI.