Macdonald gained his medical qualifications from the University of London in 1950 and held resident appointments in London and Preston. From 1968 Macdonald was consultant surgeon at Wythenshawe Hospital, and from 1982 was chairman of the medical executive committee of the Hospital. In 1980 Macdonald became honorary lecturer in surgery at the University of Manchester, and from 1983 was honorary associate lecturer.
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