The manuscript contains two different sets of lecture notes from the same teaching session, one of lectures on anatomy and physiology given by Thomas Turner (1793-1873) and one of lectures on surgery given by Joseph Atkinson Ransome (1805-1867). None of the lectures are individually numbered but there is some attempt at dating, although it is not always very clear.
Turner's lectures cover ff.1-67 and the subjects addressed as you progress through the notes include: natural objects divisible into inorganic or organic, distinction between and properties of the two groups, affinity & repulsion, caloric, stages of life, irritability, two kinds of life of animals, conditions of life, anatomy of passive life, development of active life in vegetables, what is the egg?, development of the ovum, foetal circulation, laws and principles maintaining active life, development of man passes through stages which correspond with permanent condition of lower animals, arrangement of the animal kingdom, animal part of bone, elements of the human body, elementary substances, the fluids, the lymph, the chyle, blood, cuticle, enamel of the teeth, organised textures, lymphatics, elastic membrane, inelastic membrane, elastic solid or cartilage, inelastic solid, mucous membrane, muscular tissue, measurement of the pelvis, composition of bone and animal matter, mollities ossium [osteomalacia], long bones, short bones, flat bones, irregular bones, compact structure of bone, growth of bone, and repairing injury to the bone. These notes ask a number of questions about the structure and formation of life with Turner offering his own opinions and also detailing the thoughts of his contemporaries, especially in relation to the final section on bones. Specific examples and experiments are used throughout to explain the processes and ideas he describes.
Ransome's lectures cover ff.68-254 and the subjects addressed as you progress through the notes include: general view of physiology of health, nutrition, digestion, pepsin to chyme to chyle before forming part of the blood, nutrition within the capillaries, principle of life, nutrition of the brain, nervous system, sympathetic system, chemical character of the blood, deviations from health, irritation, variations in pulse, symptoms indicated by the tongue, rigor, constitutional irritation, cold, inflammation, four symptoms of inflammation (pain, heat, redness, swelling), symptoms, treatment, remote & predisposing causes of inflammation, gangrenous inflammation, adhesive inflammation, subacute & chronic inflammation, various forms of ulcers and ulceration, scirrhous & cephaloma, mode of production of morbid growths, diseases of mechanism, modes of death, temperaments (sanguine, phlegmatic, bilious, melancholic, nervous), scrofulous tumours, erysipelas, scirrhous & cancer, tumours [neoplasms] (he omitted one lecture), bones & their diseases (caries & ulceration, necrosis, exostosis, interstitial absorption of bone, rickets, curvature of the spine), diseases of joints (wounds, ankylosis, hydrops articuli [hydrarthrosis], psoas & lumbar abscesses, bursae), diseases & injuries of arteries, diseases of absorbents, injuries of the head (concussion, fractures of the skull, simple and compressed, trephining), wounds of the face, suppuration, malignant tumours, order of temporary teeth, suppuration of tonsils, stricture of oesophagus, stomach pump, suffocation from foreign bodies, hernia. When exploring each phenomenon the notes tend to go into detail about the possible causes, pathology, diagnosis, and potential treatments, as well as offering information on the varying views and ideas of contemporary physicians.
There are a number of drawings and small illustrations to accompany and explain certain points throughout the notes from Turner's lectures and a small number in Ransome's lectures also.
Inscriptions in the front cover indicate that the manuscript was donated to the Manchester Medical Society in 1882 and subsequently allocated the reference GO 5730 viz. their 1890 library catalogue.