Mothersole was educated at Guy's Hospital, London. He spent his entire professional career in Bolton, where he was a consultant surgeon at Bolton Infirmary. He was a member of MMS and Manchester Surgical Society, and was chairman of the Bolton Division of BMA from 1922-6 and 1928-34, and was president of the Lancashire and Cheshire branch in 1932-3.
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- ReferenceGB 133 MMC/2/Mothersole
- Physical Description1 file